Serveur d'exploration sur le lymphœdème

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Podoplanin requires sialylated O-glycans for stable expression on lymphatic endothelial cells and for interaction with platelets

Identifieur interne : 002685 ( Main/Exploration ); précédent : 002684; suivant : 002686

Podoplanin requires sialylated O-glycans for stable expression on lymphatic endothelial cells and for interaction with platelets

Auteurs : Yanfang Pan [États-Unis, République populaire de Chine] ; Tadayuki Yago [États-Unis] ; Jianxin Fu [États-Unis, République populaire de Chine] ; Brett Herzog [États-Unis] ; J. Michael Mcdaniel [États-Unis] ; Padmaja Mehta-D Ouza [États-Unis] ; Xiaofeng Cai [États-Unis] ; Changgeng Ruan [République populaire de Chine] ; Rodger P. Mcever [États-Unis] ; Christopher West [États-Unis] ; Kesheng Dai [République populaire de Chine] ; Hong Chen [États-Unis] ; Lijun Xia [États-Unis, République populaire de Chine]

Source :

RBID : PMC:4256915

Abstract

Key Points

Sialylated O-glycans protects PDPN from proteolytic degradation.

Sialylated core 1 O-glycans of PDPN on lymphatic endothelial cells (LECs) are required for interacting with platelets.


Url:
DOI: 10.1182/blood-2014-04-572107
PubMed: 25336627
PubMed Central: 4256915


Affiliations:


Links toward previous steps (curation, corpus...)


Le document en format XML

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<author>
<name sortKey="Xia, Lijun" sort="Xia, Lijun" uniqKey="Xia L" first="Lijun" last="Xia">Lijun Xia</name>
<affiliation wicri:level="2">
<nlm:aff id="aff1">Cardiovascular Biology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK;</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Oklahoma</region>
</placeName>
<wicri:cityArea>Cardiovascular Biology Research Program, Oklahoma Medical Research Foundation, Oklahoma City</wicri:cityArea>
</affiliation>
<affiliation wicri:level="2">
<nlm:aff id="aff2">Department of Biochemistry and Molecular Biology, University of Oklahoma Health Sciences Center, Oklahoma City, OK;</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Oklahoma</region>
</placeName>
<wicri:cityArea>Department of Biochemistry and Molecular Biology, University of Oklahoma Health Sciences Center, Oklahoma City</wicri:cityArea>
</affiliation>
<affiliation wicri:level="1">
<nlm:aff id="aff4">Jiangsu Institute of Hematology, Collaborative Innovation Center of Hematology, Key Laboratory of Thrombosis and Hemostasis of Ministry of Health, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China</nlm:aff>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Jiangsu Institute of Hematology, Collaborative Innovation Center of Hematology, Key Laboratory of Thrombosis and Hemostasis of Ministry of Health, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu</wicri:regionArea>
<wicri:noRegion>Jiangsu</wicri:noRegion>
</affiliation>
</author>
</analytic>
<series>
<title level="j">Blood</title>
<idno type="ISSN">0006-4971</idno>
<idno type="eISSN">1528-0020</idno>
<imprint>
<date when="2014">2014</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc>
<textClass></textClass>
</profileDesc>
</teiHeader>
<front>
<div type="abstract" xml:lang="en">
<title>Key Points</title>
<p>
<list list-type="bullet">
<list-item>
<p>Sialylated
<italic>O</italic>
-glycans protects PDPN from proteolytic degradation.</p>
</list-item>
<list-item>
<p>Sialylated core 1
<italic>O</italic>
-glycans of PDPN on lymphatic endothelial cells (LECs) are required for interacting with platelets.</p>
</list-item>
</list>
</p>
</div>
</front>
</TEI>
<affiliations>
<list>
<country>
<li>République populaire de Chine</li>
<li>États-Unis</li>
</country>
<region>
<li>Oklahoma</li>
</region>
</list>
<tree>
<country name="États-Unis">
<region name="Oklahoma">
<name sortKey="Pan, Yanfang" sort="Pan, Yanfang" uniqKey="Pan Y" first="Yanfang" last="Pan">Yanfang Pan</name>
</region>
<name sortKey="Cai, Xiaofeng" sort="Cai, Xiaofeng" uniqKey="Cai X" first="Xiaofeng" last="Cai">Xiaofeng Cai</name>
<name sortKey="Chen, Hong" sort="Chen, Hong" uniqKey="Chen H" first="Hong" last="Chen">Hong Chen</name>
<name sortKey="Chen, Hong" sort="Chen, Hong" uniqKey="Chen H" first="Hong" last="Chen">Hong Chen</name>
<name sortKey="Fu, Jianxin" sort="Fu, Jianxin" uniqKey="Fu J" first="Jianxin" last="Fu">Jianxin Fu</name>
<name sortKey="Herzog, Brett" sort="Herzog, Brett" uniqKey="Herzog B" first="Brett" last="Herzog">Brett Herzog</name>
<name sortKey="Herzog, Brett" sort="Herzog, Brett" uniqKey="Herzog B" first="Brett" last="Herzog">Brett Herzog</name>
<name sortKey="Mcdaniel, J Michael" sort="Mcdaniel, J Michael" uniqKey="Mcdaniel J" first="J. Michael" last="Mcdaniel">J. Michael Mcdaniel</name>
<name sortKey="Mcever, Rodger P" sort="Mcever, Rodger P" uniqKey="Mcever R" first="Rodger P." last="Mcever">Rodger P. Mcever</name>
<name sortKey="Mcever, Rodger P" sort="Mcever, Rodger P" uniqKey="Mcever R" first="Rodger P." last="Mcever">Rodger P. Mcever</name>
<name sortKey="Mehta D Ouza, Padmaja" sort="Mehta D Ouza, Padmaja" uniqKey="Mehta D Ouza P" first="Padmaja" last="Mehta-D Ouza">Padmaja Mehta-D Ouza</name>
<name sortKey="Pan, Yanfang" sort="Pan, Yanfang" uniqKey="Pan Y" first="Yanfang" last="Pan">Yanfang Pan</name>
<name sortKey="West, Christopher" sort="West, Christopher" uniqKey="West C" first="Christopher" last="West">Christopher West</name>
<name sortKey="Xia, Lijun" sort="Xia, Lijun" uniqKey="Xia L" first="Lijun" last="Xia">Lijun Xia</name>
<name sortKey="Xia, Lijun" sort="Xia, Lijun" uniqKey="Xia L" first="Lijun" last="Xia">Lijun Xia</name>
<name sortKey="Yago, Tadayuki" sort="Yago, Tadayuki" uniqKey="Yago T" first="Tadayuki" last="Yago">Tadayuki Yago</name>
</country>
<country name="République populaire de Chine">
<noRegion>
<name sortKey="Pan, Yanfang" sort="Pan, Yanfang" uniqKey="Pan Y" first="Yanfang" last="Pan">Yanfang Pan</name>
</noRegion>
<name sortKey="Dai, Kesheng" sort="Dai, Kesheng" uniqKey="Dai K" first="Kesheng" last="Dai">Kesheng Dai</name>
<name sortKey="Fu, Jianxin" sort="Fu, Jianxin" uniqKey="Fu J" first="Jianxin" last="Fu">Jianxin Fu</name>
<name sortKey="Ruan, Changgeng" sort="Ruan, Changgeng" uniqKey="Ruan C" first="Changgeng" last="Ruan">Changgeng Ruan</name>
<name sortKey="Xia, Lijun" sort="Xia, Lijun" uniqKey="Xia L" first="Lijun" last="Xia">Lijun Xia</name>
</country>
</tree>
</affiliations>
</record>

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